BDBM50185047 CHEMBL3822907

SMILES COc1ccc(cc1)-c1coc2c(c(O)cc3occ(-c4ccc(OC)cc4)c(=O)c23)c1=O

InChI Key InChIKey=TWCHPOVZCCAPMG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50185047   

TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185047(CHEMBL3822907)
Affinity DataIC50: 303nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185047(CHEMBL3822907)
Affinity DataIC50: 79nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185047(CHEMBL3822907)
Affinity DataIC50: 577nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185047(CHEMBL3822907)
Affinity DataIC50: 500nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185047(CHEMBL3822907)
Affinity DataIC50: 576nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185047(CHEMBL3822907)
Affinity DataIC50: 544nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed