BDBM50185028 CHEMBL3823024

SMILES Cc1cccc(c1)-c1coc2c(c(O)cc3occ(-c4cccc(C)c4)c(=O)c23)c1=O

InChI Key InChIKey=YODNETMUXGRYDW-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50185028   

TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 96nMAssay Description:Inhibition of ABCB1 in human KBVIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 10 uM after 72...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 40nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 53nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 39nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 664nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 586nMAssay Description:Inhibition of full length human ABCB1 expressed in Flp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 63nMAssay Description:Inhibition of ABCB1 in human KBVIN cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 8 uM after 72 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 52nMAssay Description:Inhibition of ABCB1 in human KBVIN cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 10 uM after 72 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50185028(CHEMBL3823024)
Affinity DataIC50: 390nMAssay Description:Inhibition of ABCB1 in human KBVIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 8 uM after 72 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed