BDBM50184914 1-((1S,2R,5S)-5-(3-aminophenyl)bicyclo[3.1.0]hexan-2-yl)-3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazin-1-yl)propyl)urea::CHEMBL382841::N-[trans-5-(3-aminophenyl)bicyclo[3.1.0]hex-2-yl]-N'-(3-chloro-4-fluorophenyl)-N-[3-(4-methyl-1-piperazinyl)propyl]urea

SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2cccc(N)c2)C(=O)Nc2ccc(F)c(Cl)c2)CC1

InChI Key InChIKey=XNXZHSREQUABAF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184914   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184914(1-((1S,2R,5S)-5-(3-aminophenyl)bicyclo[3.1.0]hexan...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184914(1-((1S,2R,5S)-5-(3-aminophenyl)bicyclo[3.1.0]hexan...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed