BDBM50184880 1-(4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)phenoxy)propan-2-one::1-[(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}phenyl)-oxy]-2-propanone::CHEMBL202943

SMILES CC(=O)COc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key InChIKey=NMDWFWYMBJVIQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184880   

TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50184880(1-[(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridi...)
Affinity DataIC50: 25nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50184880(1-[(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridi...)
Affinity DataIC50: 25nMAssay Description:Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed