BDBM50184862 CHEMBL204409::N-Benzyl-N'-{4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl}-thiourea

SMILES COc1cc2ncnc(Oc3ccc(NC(=S)NCc4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=COGIYNUARZWUAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184862   

TargetPlatelet-derived growth factor receptor alpha(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184862(N-Benzyl-N'-{4-[(6,7-dimethoxy-4-quinazolinyl)oxy]...)
Affinity DataIC50: 46nMAssay Description:Inhibition of PDGFR alpha phosphorylation in G292 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50184862(N-Benzyl-N'-{4-[(6,7-dimethoxy-4-quinazolinyl)oxy]...)
Affinity DataIC50: 303nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed