BDBM50184797 1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine::1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine::CHEMBL437490

SMILES Fc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccccc2)CC1

InChI Key InChIKey=ZQEBKQUIKOLFRO-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50184797   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in Wistar rat hippocampus homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2(short) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2(long) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Wistar rat cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50184797(1-(4-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)me...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptor in porcine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed