BDBM50184743 2-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethyl)pyridin-2-yl)-1,2-dihydroindazol-3-one::CHEMBL3144709

SMILES FC(F)(F)c1ccc(cc1)-n1[nH]c2ccc(cc2c1=O)-c1ncccc1C(F)(F)F

InChI Key InChIKey=VGTMEUVXBNRDPP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184743   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharp & Dohme

Curated by ChEMBL

LigandBDBM50184743(2-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethy...)Copy SMILESCopy InChI

Affinity DataIC50: 370nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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