BDBM50184734 6-(3-methylpyridin-2-yl)-2-(4-(trifluoromethyl)phenyl)-1,2-dihydropyrazolo[3,4-b]pyridin-3-one::CHEMBL3144708

SMILES Cc1cccnc1-c1ccc2c(n1)[nH]n(-c1ccc(cc1)C(F)(F)F)c2=O

InChI Key InChIKey=JBKBYCPLTXERTR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184734   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharp & Dohme

Curated by ChEMBL

LigandBDBM50184734(6-(3-methylpyridin-2-yl)-2-(4-(trifluoromethyl)phe...)Copy SMILESCopy InChI

Affinity DataIC50: 270nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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