BDBM50184729 2-(4-(trifluoromethyl)phenyl)-6-(3-(trifluoromethyl)pyridin-2-yl)-1,2-dihydroindazol-3-one::CHEMBL3144710
SMILES FC(F)(F)c1ccc(cc1)-n1[nH]c2cc(ccc2c1=O)-c1ncccc1C(F)(F)F
InChI Key InChIKey=XZTHIRNRCYWVIO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50184729
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataIC50: 4nMpH: 5.5Assay Description:Inhibition of acidic pH 5.5-stimulated current in CHO cells expressing human TRPV1 receptor by patch clampMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing rat TRPV1 assessed by patch clampMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing rat TRPV1 assessed by patch clampMore data for this Ligand-Target Pair
