BDBM50184586 CHEMBL208936::rac-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole

SMILES FC(F)(F)c1ccnc(n1)N1CCC2CNCC12

InChI Key InChIKey=LGUHTSNWHUTCTC-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184586   

Target5-hydroxytryptamine receptor 2B(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(rac-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydr...)
Affinity DataEC50:  320nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(rac-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydr...)
Affinity DataEC50:  220nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50184586(rac-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydr...)
Affinity DataEC50:  180nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed