BDBM50184584 (3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-octahydropyrrolo[3,4-b]pyrrole::CHEMBL210802

SMILES FC(F)(F)c1ccnc(n1)N1CC[C@H]2CNC[C@@H]12

InChI Key InChIKey=LGUHTSNWHUTCTC-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184584   

Target5-hydroxytryptamine receptor 2B(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  62nMAssay Description:Induction of 5HT2B receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  116nMAssay Description:Induction of 5HT2A receptor mediated increase in intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50184584((3aS,6aS)-1-(4-(trifluoromethyl)pyrimidin-2-yl)-oc...)
Affinity DataEC50:  23nMAssay Description:Induction of 5HT2C receptor mediated increase in intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed