BDBM50184276 3-(1-hydroxy-3,3-dimethyl-3,4,10,11-tetrahydro-2H-dibenzo[b,e][1,4]diazepin-11-yl)-benzene-1,2-diol::CHEMBL208433

SMILES CC1(C)CC(=O)C2C(Nc3ccccc3N=C2C1)c1cccc(O)c1O

InChI Key InChIKey=RLDJDBCCYQMCLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184276   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50184276(3-(1-hydroxy-3,3-dimethyl-3,4,10,11-tetrahydro-2H-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Hsp90 by recombinant ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50184276(3-(1-hydroxy-3,3-dimethyl-3,4,10,11-tetrahydro-2H-...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of Her2 in SKBr3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed