BDBM50183552 CHEMBL412331::H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-Trp-Ac

SMILES CCCC[C@H](N(C(=O)Nc1ccccc1Cl)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)N(C)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@@H](Cc1cn(C(C)=O)c2ccccc12)C(O)=O

InChI Key InChIKey=ZICGXQSIIFWORG-UHFFFAOYSA-N

Data  5 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50183552   

TargetGastrin/cholecystokinin type B receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataIC50: 1.74E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataEC50:  14nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataEC50:  14nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataIC50: 200nMAssay Description:Agonist activity at mu opioid receptor by inhibition of muscle contraction in electrically stimulated isolated guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataIC50: 26nMAssay Description:Agonist activity at delta opioid receptor by inhibition of muscle contraction in electrically stimulated isolated mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataKi:  0.920nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50183552(H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-T...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [125I]CCK8 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed