BDBM50183503 5,6-dihydroxy-2-pyrazin-2-ylpyrimidine-4-carboxylic acid::CHEMBL205130

SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cnccn1

InChI Key InChIKey=UUPPOBBBMAWWMW-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183503   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM50183503(5,6-dihydroxy-2-pyrazin-2-ylpyrimidine-4-carboxyli...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50183503(5,6-dihydroxy-2-pyrazin-2-ylpyrimidine-4-carboxyli...)
Affinity DataEC50:  3.80E+3nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50183503(5,6-dihydroxy-2-pyrazin-2-ylpyrimidine-4-carboxyli...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to PA N-terminal domain (Competitive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed