BDBM50183374 CHEMBL3818972

SMILES COc1cccc(OC)c1-c1cc(nn1-c1ccc(F)cc1)C(=O)N[C@@H](CCc1ccccc1)CC(O)=O

InChI Key InChIKey=BKIKIBZQDFIDCV-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183374   

TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50183374(CHEMBL3818972)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human APJ receptor expressed in cells c-expressing Galphaq16 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50183374(CHEMBL3818972)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [125I]-apelin13 from human APJ receptor expressed in CHOK1 cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed