BDBM50183343 CHEMBL3818506

SMILES COc1cccc(OC)c1-c1cc(nn1-c1ccc(F)cc1)C(=O)N[C@H](CC(O)=O)C1CCCCC1

InChI Key InChIKey=VHQDBWUQVXLXFT-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183343   

TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50183343(CHEMBL3818506)
Affinity DataEC50:  9.90E+3nMAssay Description:Agonist activity at human APJ receptor expressed in cells c-expressing Galphaq16 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Rti International

Curated by ChEMBL
LigandPNGBDBM50183343(CHEMBL3818506)
Affinity DataEC50:  345nMAssay Description:Partial agonist activity at rat NTS2 receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetApelin receptor(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50183343(CHEMBL3818506)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [125I]-apelin13 from human APJ receptor expressed in CHOK1 cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed