BDBM50183227 1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-yl)propyl)naphthalen-2-yloxy)methyl)cyclobutanecarboxylic acid::CHEMBL207345

SMILES C[C@H]([C@@H](c1ccc2cc(OCC3(CCC3)C(O)=O)ccc2c1)n1ccnc1)N(C)C

InChI Key InChIKey=WNMJTTIGNYLSJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183227   

TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183227(1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183227(1-((6-((1R,2R)-2-(dimethylamino)-1-(1H-imidazol-1-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP26 expressed in human T47D cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed