BDBM50183201 CHEMBL379722::N-(2-chloro-4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimethyl-phenyl)-1H-tetrazol-5-ylsulfanyl]-acetamide

SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1Cl)S(N)(=O)=O

InChI Key InChIKey=UBXXFDJETHMQAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50183201   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50183201(N-(2-chloro-4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimet...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 wild type Reverse TranscriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183201(N-(2-chloro-4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimet...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183201(N-(2-chloro-4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimet...)
Affinity DataIC50: 35nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183201(N-(2-chloro-4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimet...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed