BDBM50182898 CHEMBL206782::methyl 5-(3-(2-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)pyrimidin-5-yl)ethynyl)phenylamino)-5-oxopentanoate

SMILES COC(=O)CCCC(=O)Nc1cccc(c1)C#Cc1cncnc1Nc1ccc(OCc2cccc(F)c2)c(Cl)c1

InChI Key InChIKey=SMSOSQRBSNFBDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182898   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182898(methyl 5-(3-(2-(4-(4-(3-fluorobenzyloxy)-3-chlorop...)
Affinity DataIC50: 29nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182898(methyl 5-(3-(2-(4-(4-(3-fluorobenzyloxy)-3-chlorop...)
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed