BDBM50182501 4-ethyl-6-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-diol::CHEMBL381149

SMILES CCc1cc(-c2n[nH]cc2Oc2ccccc2)c(O)cc1O

InChI Key InChIKey=CNJFYVMPHWHMIT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182501   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50182501(4-ethyl-6-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-d...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of 15-hLOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50182501(4-ethyl-6-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-d...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50182501(4-ethyl-6-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-d...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human 15-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50182501(4-ethyl-6-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-d...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human platelet-type 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed