BDBM50182491 CHEBI:69015::Malabaricone C
SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1O
InChI Key InChIKey=HCOZRFYGIFMIEX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50182491
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a...More data for this Ligand-Target Pair
TargetAlbumin(Bovine)
Csir-National Institute For Interdisciplinary Science and Technology
Curated by ChEMBL
Csir-National Institute For Interdisciplinary Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Antiglycation activity in bovine serum albumin assessed as inhibition of advanced glycated end product formation after 24 hrs in presence of alpha-D-...More data for this Ligand-Target Pair
TargetPancreatic alpha-amylase(Pig)
Csir-National Institute For Interdisciplinary Science and Technology
Curated by ChEMBL
Csir-National Institute For Interdisciplinary Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate after 30 mins by iodine reagent based assayMore data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Mouse)
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of SMS2 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Mouse)
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of SMS1 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...More data for this Ligand-Target Pair
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Hokkaido University
Curated by ChEMBL
Hokkaido University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
TargetSialidase A(Streptococcus pneumoniae)
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Competitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mi...More data for this Ligand-Target Pair
Affinity DataKi: 5.86E+3nMAssay Description:Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+4nMAssay Description:Mixed inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair