BDBM50182487 Malabaricone A

SMILES Oc1cccc(O)c1C(=O)CCCCCCCCc1ccccc1

InChI Key InChIKey=IAXIHKJASWPASP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50182487   

TargetAcetylcholinesterase(Human)
University of Malaya

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Malaya

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetAlbumin(Bovine)
Csir-National Institute For Interdisciplinary Science and Technology

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 1.93E+4nMAssay Description:Antiglycation activity in bovine serum albumin assessed as inhibition of advanced glycated end product formation after 24 hrs in presence of alpha-D-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
Csir-National Institute For Interdisciplinary Science and Technology

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate after 30 mins by iodine reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 1.00E+3nMAssay Description:Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50: 2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed