BDBM50182438 CHEMBL3819113

SMILES COc1ccc2C\C(=C/C3CCN(Cc4cccc(OC)c4)CC3)C(=O)c2c1

InChI Key InChIKey=VRHAQRBXZOTBMX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182438   

TargetAcetylcholinesterase(Human)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182438(CHEMBL3819113)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182438(CHEMBL3819113)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182438(CHEMBL3819113)
Affinity DataKi:  3.89E+3nMAssay Description:Non-competitive inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182438(CHEMBL3819113)
Affinity DataKi:  1.19E+5nMAssay Description:Non-competitive inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed