BDBM50182433 CHEMBL3819155

SMILES COc1cc2C(=O)\C(Cc2cc1O)=C\C1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=ZEAXIVSYMLISJH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182433   

TargetAcetylcholinesterase(Human)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182433(CHEMBL3819155)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182433(CHEMBL3819155)
Affinity DataIC50: 7.35E+3nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182433(CHEMBL3819155)
Affinity DataKi:  2.82E+3nMAssay Description:Non-competitive inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Magna Graecia University of Catanzaro

Curated by ChEMBL
LigandPNGBDBM50182433(CHEMBL3819155)
Affinity DataKi:  1.06E+4nMAssay Description:Non-competitive inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed