BDBM50182404 CHEMBL3819371

SMILES Cc1cncc(n1)-c1ccc(c(Cl)c1)-c1cc2cncnc2n(C[C@H]2CC[C@H](N)CC2)c1=O

InChI Key InChIKey=GEEQAZJUJDNBFD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182404   

TargetSerine/threonine-protein kinase PAK 1(Human)
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50182404(CHEMBL3819371)
Affinity DataKi:  372nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Shanghai Chempartner

Curated by ChEMBL
LigandPNGBDBM50182404(CHEMBL3819371)
Affinity DataKi:  940nMAssay Description:Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed