BDBM50182259 CHEMBL3819603

SMILES CC(C)N1CCN(CC1)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O

InChI Key InChIKey=PMHBKUTXIPSEAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182259   

TargetC-X-C chemokine receptor type 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50182259(CHEMBL3819603)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human recombinant Gal4-VP16 fused-CXCR2 assessed as inhibition of CXCL1-mediated lactamase reporter gene expression after over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50182259(CHEMBL3819603)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human recombinant CXCR2 assessed as inhibition of CXCL1-induced neutrophil chemotaxis after 45 mins by calcein-AM dye based pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details Article
PubMed