BDBM50182135 3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroisoxazole::CHEMBL208485

SMILES COc1c(ccc2occc12)C1=NOC(C1)c1ccccc1

InChI Key InChIKey=USHIACGOJWXTMQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182135   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataIC50: 2.27E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataIC50: 7.60E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2013
Entry Details Article

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed