BDBM50182060 CHEMBL204670::N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro-benzoyl}-N'-[4-(methyl-naphthalen-1-ylmethyl-amino)-butyl]-guanidine

SMILES COc1ccc(Br)cc1CCc1c(F)cccc1C(=O)NC(N)=NCCCCN(C)Cc1cccc2ccccc12

InChI Key InChIKey=NTSIGIWMFNKJSL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182060   

TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182060(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182060(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  57nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed