BDBM50181746 3-[5-[(2-methyl-4-thiazolyl)ethynyl]-3-pyridyl]-2-propyn-1-ol::CHEMBL382658

SMILES Cc1nc(cs1)C#Cc1cncc(c1)C#CCO

InChI Key InChIKey=BJHXXZFLVMWWEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181746   

TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181746(3-[5-[(2-methyl-4-thiazolyl)ethynyl]-3-pyridyl]-2-...)
Affinity DataIC50: 68.6nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed