BDBM50181742 2-chloro-3-[(2-methyl-4-thiazolyl)ethynyl]pyridine::CHEMBL383771

SMILES Cc1nc(cs1)C#Cc1cccnc1Cl

InChI Key InChIKey=QLWMJSFCHZCXRN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181742   

TargetMetabotropic glutamate receptor 5(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181742(2-chloro-3-[(2-methyl-4-thiazolyl)ethynyl]pyridine...)
Affinity DataIC50: 45.5nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed