BDBM50181650 1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]-thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one::CHEMBL202319

SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccccc12

InChI Key InChIKey=WQCGANAJIIVGSB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181650   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181650(1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181650(1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-...)
Affinity DataEC50:  152nMAssay Description:Inhibition of HCV RNA replication in Huh7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed