BDBM50181608 CHEMBL202310::[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-dihydroquinolin-6-ylamino]acetic acid ethyl ester

SMILES CCOC(=O)CNc1ccc2n(CCC(C)C)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1

InChI Key InChIKey=OGFBGXULTNAQFC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181608   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181608([3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-...)
Affinity DataIC50: 115nMAssay Description:Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181608([3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-...)
Affinity DataEC50:  265nMAssay Description:Inhibition of HCV RNA replication in Huh7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed