BDBM50180978 CHEMBL3819515

SMILES FC(F)Oc1cccc(N\C(=N\C#N)N2CC(N3CNCC3=O)C(=N2)c2ccc(Cl)cc2)c1

InChI Key InChIKey=MLGIGZIVNMAVEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180978   

TargetN-lysine methyltransferase SMYD2(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180978(CHEMBL3819515)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180978(CHEMBL3819515)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed