BDBM50180775 CHEMBL386763::FV-Aib-TDVGPFAF::[Aib29,Asp31,Pro34,Phe35]CGRP(27-37)

SMILES CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=GUILBDPDYMIGBQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180775   

TargetCalcitonin gene-related peptide 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50180775([Aib29,Asp31,Pro34,Phe35]CGRP(27-37) | FV-Aib-TDVG...)
Affinity DataIC50: 740nMAssay Description:Antagonist activity at human CGRP1 receptor in human SK-N-MC cells assessed as effect on human alpha-CGRP-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50180775([Aib29,Asp31,Pro34,Phe35]CGRP(27-37) | FV-Aib-TDVG...)
Affinity DataKi:  0.00200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed