BDBM50180652 CHEMBL3819527

SMILES CN1CCN(CC(=O)N2N=C3C(CCC\C3=C/c3ccccc3)C2c2ccccc2)CC1

InChI Key InChIKey=GEMFAWUXUVGGTE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180652   

TargetProstaglandin E synthase(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50180652(CHEMBL3819527)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mPGES-1 (unknown origin) assessed as reduction in conversion of PGH2 to PGE2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50180652(CHEMBL3819527)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to wild-type His6-tagged human 15-LOX expressed in Escherichia coli Rosetta DE3 by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed