BDBM50180432 (8-Chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-(3-chloro-4-fluoro-phenyl)-amine::CHEMBL205676

SMILES Fc1ccc(Nc2ncnc3Oc4ccc(Cl)cc4CNc23)cc1Cl

InChI Key InChIKey=IVJCIKOHVJLJMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180432   

TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180432((8-Chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibenz...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180432((8-Chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibenz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed