BDBM50180177 1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N-cyclobutylmethylmorphinan-3-yl) sebacoylate::CHEMBL193039

SMILES O=C(CCCCCCCCC(=O)Oc1ccc2C[C@H]3C4CCCC[C@@]4(CCN3CC3CCC3)c2c1)Oc1ccc2C[C@@H]3C4CCCC[C@]4(CCN3CC3CCC3)c2c1

InChI Key InChIKey=LWMXWHIOMHIBJP-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50180177   

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataIC50: 460nMAssay Description:Activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataEC50:  7.90nMAssay Description:Activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed