BDBM50180022 5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1H-pyrazole-3-carboxylic acid (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide::CHEMBL381689
SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 65 hits for monomerid = 50180022
Affinity DataIC50: 3.20nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 741nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
Affinity DataEC50: 13.7nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cells assessed as increase in forskolin-induced cAMP accumulation incubated for 45 mi...More data for this Ligand-Target Pair
Affinity DataEC50: 10.4nMAssay Description:Agonist activity at human CB2 receptor expressed CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human CB2 receptor after 1 hr by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Inverse agonist activity at CB2 receptor (unknown origin) expressed in HEK cells assessed as increase in cAMP production measured at 50 mins by ACTOn...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-stimulated cAMP production after 4...More data for this Ligand-Target Pair
Affinity DataEC50: 154nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cells assessed as increase in forskolin-induced cAMP production after 45 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [35S]GTP-gamma-S binding to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]-CP-55,940 from CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]-CP-55940 from cannabinoid CB2 receptor in CD1 mouse spleen membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]CP-55940 from CD1 mouse spleen CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in HEK293T cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]CP55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:HEK293DHEK293iHEK293sHEK293pHEK293lHEK293aHEK293cHEK293eHEK293mHEK293eHEK293nHEK293tHEK293 HEK293oHEK293fHEK293 HEK293[HEK2933HEK293HHEK293]HEK293CHE...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at cloned human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]CP-55,940 from human frontal cortex CB2 receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Antagonist activity at rat spleen CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]CP55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55,940 from CB2 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor transfected in HEK cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55,940 from recombinant human CB2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-CP55940 from CB2 receptor (unknown origin) expressed in CHO cell membranes after 90 mins by liquid scintillation counting analys...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21.6nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 51.7nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 51.7nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]-CP-55,940 from CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]-CP-55940 from cannabinoid CB1 receptor in CD1 mouse brain membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP-55940 from CD1 mouse brain CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Displacement of [3H]CP-55,940 from rat brain CB1 receptor after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Displacement of [3H]CP-55,940 from human U937 cell-derived CB1 receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 437nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 437nMAssay Description:Antagonist activity at rat brain CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 437nMAssay Description:Antagonist activity at cloned human CB1 receptorMore data for this Ligand-Target Pair