BDBM50179757 CHEMBL205776::N-(3-chloro-4-fluorophenyl)-7-(3-(4-methylpiperazin-1-yl)propoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine

SMILES CN1CCN(CCCOc2cc(OC3CCOCC3)c3c(Nc4ccc(F)c(Cl)c4)ncnc3c2)CC1

InChI Key InChIKey=UYNGIWGAHXGANL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179757   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50179757(N-(3-chloro-4-fluorophenyl)-7-(3-(4-methylpiperazi...)
Affinity DataIC50: 66nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed