BDBM50179414 2-(6-(4-(2-morpholinoethyl)piperazin-1-yl)pyrimidin-4-ylamino)thiazole-5-carbonitrile::CHEMBL204446

SMILES N#Cc1cnc(Nc2cc(ncn2)N2CCN(CCN3CCOCC3)CC2)s1

InChI Key InChIKey=YOARXMDDBVYHOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179414   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179414(2-(6-(4-(2-morpholinoethyl)piperazin-1-yl)pyrimidi...)
Affinity DataIC50: 12nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179414(2-(6-(4-(2-morpholinoethyl)piperazin-1-yl)pyrimidi...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human KDR expressed in HEK293 cells by KDR autophosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed