BDBM50179088 CHEMBL2286725

SMILES Cc1ccc(C)c(c1)C(=O)NN(C(=O)c1ccccc1Cl)C(C)(C)C

InChI Key InChIKey=ZGQJECISIKVETQ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50179088   

TargetATP-dependent translocase ABCB1(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50179088(CHEMBL2286725)
Affinity DataIC50: 7.36E+4nMAssay Description:Inhibition of human P-glycoprotein transfected in pig LLC-GA5-COL150 cells assessed as quinidine transport from apical to basolateral side preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2017
Entry Details Article
PubMed
TargetProtein ultraspiracle(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50179088(CHEMBL2286725)
Affinity DataEC50:  1.07E+5nMAssay Description:Agonist activity at ecdysone receptor in Drosophila melanogaster S2 cells after 24 hr by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEcdysone receptor(Silk moth)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50179088(CHEMBL2286725)
Affinity DataEC50:  1.62E+3nMAssay Description:Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed