BDBM50179047 1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl)-9H-purin-6-yl)-3-(4-propoxyphenyl)urea::CHEMBL206807

SMILES CCCOc1ccc(NC(=O)Nc2ncnc3n(cnc23)[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)C(=O)NCC)cc1

InChI Key InChIKey=ALQXBWHXWIDDKS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50179047   

TargetAdenosine receptor A3(Rat)
Vigo University

Curated by ChEMBL
LigandPNGBDBM50179047(1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydro...)
Affinity DataKi:  107nMAssay Description:Displacement of [125I]AB-MECA from rat adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
Vigo University

Curated by ChEMBL
LigandPNGBDBM50179047(1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydro...)
Affinity DataKi:  107nMAssay Description:Binding affinity against rat adenosine A3 receptor expressed in CHO cells using [125I]-.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Rat)
Vigo University

Curated by ChEMBL
LigandPNGBDBM50179047(1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydro...)
Affinity DataKi:  107nMAssay Description:Displacement of radioligand [125I]AB-MECA binding at rat A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50179047(1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydro...)
Affinity DataKi:  247nMAssay Description:Binding affinity against adenosine A1 receptor in rat brain membranes using [3H]R-PIA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50179047(1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydro...)
Affinity DataKi:  247nMAssay Description:Inhibition of [3H]R-PIA binding to Adenosine A1 receptor from rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50179047(1-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydro...)
Affinity DataKi:  255nMAssay Description:Binding affinity against adenosine A2A receptor in rat striatal membranes using [3H]-CGS- 21680.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed