BDBM50178844 5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)pyrazine-2-carboxamide::CHEMBL205402

SMILES Cc1cnc(cn1)C(=O)Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1

InChI Key InChIKey=QCQCMNUQTMIKHU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178844   

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 261nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 33nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 33nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed