BDBM50178827 (+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamide::(-)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamide::CHEMBL203839

SMILES Fc1ccc(Nc2cc(ccn2)-c2ccnc(NC(=O)C3CCOC3)c2)cc1

InChI Key InChIKey=DGTWHZKHMUDXOY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50178827   

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 48nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 48nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 581nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 581nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed