BDBM50178772 6-hydroxy-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL369710

SMILES NC(=O)C1CCCc2c1[nH]c1ccc(O)cc21

InChI Key InChIKey=GVGNLVXOSAAGMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178772   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Elixir Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178772(6-hydroxy-2,3,4,9-tetrahydro-1H-carbazole-1-carbox...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Elixir Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178772(6-hydroxy-2,3,4,9-tetrahydro-1H-carbazole-1-carbox...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed