BDBM50178763 3,6-bis(Dmt-Tic-NH-propyl)-2(1H)-pyrazinone::CHEMBL381874

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C

InChI Key InChIKey=NATWHSVYZBCLOS-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178763   

TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178763(3,6-bis(Dmt-Tic-NH-propyl)-2(1H)-pyrazinone | CHEM...)
Affinity DataIC50: 7.03E+3nMAssay Description:Agonistic activity at mu opioid receptor in myenteric plexus longitudinal muscle of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178763(3,6-bis(Dmt-Tic-NH-propyl)-2(1H)-pyrazinone | CHEM...)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonistic activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178763(3,6-bis(Dmt-Tic-NH-propyl)-2(1H)-pyrazinone | CHEM...)
Affinity DataKi:  0.155nMAssay Description:Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178763(3,6-bis(Dmt-Tic-NH-propyl)-2(1H)-pyrazinone | CHEM...)
Affinity DataKi:  3.08nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed