BDBM50178646 5-chloro-2-[(2-methyl-3-phenylpropanoyl)amino]benzoic acid::CHEMBL373194::US11225469, Compound 20

SMILES CC(Cc1ccccc1)C(=O)Nc1ccc(Cl)cc1C(O)=O

InChI Key InChIKey=NMVOUGNPVVJWHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178646   

TargetHolo-[acyl-carrier-protein] synthase(Bacillus subtilis (strain 168))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178646(5-chloro-2-[(2-methyl-3-phenylpropanoyl)amino]benz...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against Bacillus subtilis AcpS by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM50178646(5-chloro-2-[(2-methyl-3-phenylpropanoyl)amino]benz...)
Affinity DataIC50: 2.00E+4nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent