BDBM50178314 (3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol::CHEMBL373019

SMILES C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C=C)C1CC[C@@H]2O

InChI Key InChIKey=RRDYXHHANIMNOJ-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50178314   

TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178314((3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10...)
Affinity DataIC50: 2.24E+3nMAssay Description:Binding affinity to human ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178314((3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10...)
Affinity DataIC50: 11nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178314((3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10...)
Affinity DataEC50:  4.10nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178314((3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178314((3S,10S,13S,17S)-13-methyl-10-vinyl-2,3,4,7,8,9,10...)
Affinity DataEC50:  982nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed