BDBM50178270 CHEMBL382803::N-(2-cyclopropoxy-5-(trifluoromethoxy)benzyl)-1-phenyl-8-aza-bicyclo[3.2.1]octan-2-amine

SMILES FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3CCC2(N3)c2ccccc2)c1

InChI Key InChIKey=VBOXQXAJDAUESQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178270   

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178270(N-(2-cyclopropoxy-5-(trifluoromethoxy)benzyl)-1-ph...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-labeled substance P from cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178270(N-(2-cyclopropoxy-5-(trifluoromethoxy)benzyl)-1-ph...)
Affinity DataKi:  360nMAssay Description:Displacement of [35S]-labeled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed