BDBM50177893 CHEMBL383811::N-(2,4-difluorophenyl)-N'-heptyl-N'-{5-[(5-phenyl-pyridazin-3-yl)amino]pentyl}urea

SMILES CCCCCCCN(CCCCCNc1cc(cnn1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F

InChI Key InChIKey=FSSUYZVDYFGHCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177893   

TargetSterol O-acyltransferase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50177893(N-(2,4-difluorophenyl)-N'-heptyl-N'-{5-[(5-phenyl-...)
Affinity DataIC50: 4.14E+5nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50177893(N-(2,4-difluorophenyl)-N'-heptyl-N'-{5-[(5-phenyl-...)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of ACAT expressed in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50177893(N-(2,4-difluorophenyl)-N'-heptyl-N'-{5-[(5-phenyl-...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed